Drug Penetration and Accumulation of Drugs and Biomarker Response
Information on drug distribution and penetration in the brain is important to assess the potential activity and efficacy of drugs. We offer services of bioanalysis and spatial bioanalysis including quantitative distribution of drugs and biomarker into the brain structures using label free technique of Mass Spectrometry Imaging (Learn more), Gene Expression platform (learn more) and innovative multiplex Immuno-staining (Learn more) to assess accurate drug activities. in GLP environment, We also propose whole body imaging to measure outside the brain, some other drug accumulation and activities. Discover the fast imaging process and exclusive panel of biomarker (create your own panel) to measure quickly the potential of your drugs at a single cell level through examples and publications.
What can be achieved?
Distribution & Quantification of a drug candidate and its metabolites
Measure Gene, protein or lipids levels in a Multi-omics platform
Measure the concentration of neurotransmitters and other small biomarkers
Measure Toxicity Activities to neurons
Drug quantification combined with protein imaging (Beta Amyloid 1-42, 1-38…)
What are our advantages?
Fast Quantify drug and metabolites in different region of the brain
Robust High Multiplex Immuno-staining
Gene Expression measure and multi-omics technologies
Single cell Imaging and quantification
Where can we work?
With a GLP environment and team of experts in CNS, we can select section plans and specific orientation into the brain to measure dug and biomarkers in:
- Corpus callosum
- Blood-brain barrier
|Application Notes||Keeping an Eye on Molecular Imaging|
|Application Notes||Distribution of GABA with Mass Spectrometry Imaging|
|Publications||Mapping molecules in CNS|