What can be achieved?

Distribution & Quantification of a drug candidate and its metabolites in brain substructures

Better lead selection in comparing drug penetration with targets within the brain substructures and receptors

Quantification of drugs and metabolites in different layers of the brain

Better toxicity assessment with identification of the possible causes of toxicity in the brain

Drug quantification combined with Biomarker imaging (Beta Amyloid 1-42, 1-38…)

What are our advantages?

Quantify drug and metabolites in different region of the brain

Molecular immune-histology

Ability to overlay both molecular and spatial information within multimodal platform and software (IHC, MSI, etc…)

Efficacy and Safety Biomarkers monitoring thanks to a global approach

High Resolution Mass Spectrometers (R>200,000)

Where can we work?

  • Hippocampus
  • Cerebellum
  • Cortices
  • Corpus callosum
  • Blood-brain barrier

Brain Imaging

Resources

Application NotesPublications
Keeping an Eye on Molecular ImagingMapping molecules in CNS
Distribution of GABA with Mass Spectrometry Imaging

Testimonies

anonymous-customer

CNS project 2016

CNS, Anonymous

“….Good interactions on the project”

Contact us

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