Central Nervous System
ImaBiotech provides quantitative MALDI Imaging Mass Spectrometry services unmatched by any other classical technique: quantitative label-free CNS distribution with high accuracy up to 20µm resolution.
Classical drug pharmacokinetics, such as the evaluation of the brain/plasma ratio of molecule concentration, can now be advantageously replaced by MALDI Imaging Mass Spectrometry, which offers accurate localization and quantitation of parent drugs and metabolites. The evaluation of regio-distribution in the brain also supports studies in pharmacology and local toxicity, side effects, etc..
In the same experiment, MALDI Imaging Mass Spectrometry can also provide valuable information regarding endogenous metabolites (lipids, proteins,…) and disease markers such as amyloid peptides.